|
KMID : 1161420100130010211
|
|
Journal of Medicinal Food
2010 Volume.13 No. 1 p.211 ~ p.215
|
|
|
Antifatigue Effect of Coenzyme Q10 in Mice
|
|
Fu Xin
Ji Rong
Dam Jorgen
|
|
|
Abstract
|
|
|
|
The aim of this study was to investigate whether coenzyme Q10 (CoQ10) has an antifatigue effect in mice. ICR male mice were orally given CoQ10 in the form of Bio-Quinone® (Pharma Nord, Vejle, Denmark) at doses of 0, 1.5, 15, or 45?mg/kg/day for 4 weeks. Mice were made to perform swimming exercise with loads attached to their tails, corresponding to approximately 5% of their body weights, and the total swimming time until exhaustion was measured. Furthermore, the post-exercise concentration of serum urea nitrogen (SUN), pre-/post-exercise and post-rest concentration of lactic acid (LA), and pre-exercise hepatic glycogen were determined. Mice treated with CoQ10 showed a significantly prolonged exhaustive swim time (15?mg/kg/day; P?
|
|
|
KEYWORD
|
|
|
Bio-Quinone, endurance, fatigue, glycogen, swimming, ubiquinone
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
 
|
|